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In vivo and in vitro models of demyelinating disease X. A Schwannoma-L-2 somatic cell hybrid persistently yielding high titres of mouse hepatitis virus strain JHM

Following infection of RN2 rat Schwannoma cells with unfiltered JHMV inocula, a cell line with an altered phenotype evolved, which was shown to be a somatic cell hybrid of RN2 and mouse L-2 cells. This cell line, EJ, persistently yields JHMV at titres greater than 10(6) pfu/ml and does not show the...

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Detalles Bibliográficos
Autores principales: Coulter-Mackie, M.B., Flintoff, W.F., Dales, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 1984
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7134070/
https://www.ncbi.nlm.nih.gov/pubmed/6099665
http://dx.doi.org/10.1016/0168-1702(84)90005-4