Loss of cytomegalovirus infectivity after treatment with castanospermine or related plant alkaloids correlates with aberrant glycoprotein synthesis

Many plants contain polyhydroxyalkaloids which are potent inhibitors of glucosidases, enzymes involved in oligosaccharide trimming. These are important in determining the final configuration of specific glycoproteins. Human cytomegalovirus (CMV) encodes a number of glycoproteins, some of which ultim...

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Detalles Bibliográficos
Autores principales: Taylor, D.L., Fellows, L.E., Farrar, G.H., Nash, R.J., Taylor-Robinson, D., Mobberley, M.A., Ryder, T.A., Jeffries, D.J., Tyms, A.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 1988
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7134106/
https://www.ncbi.nlm.nih.gov/pubmed/2852915
http://dx.doi.org/10.1016/0166-3542(88)90011-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7134106/
https://www.ncbi.nlm.nih.gov/pubmed/2852915
http://dx.doi.org/10.1016/0166-3542(88)90011-3

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