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A study of the efficacy of the bradykinin antagonist, NPC 567, in rhinovirus infections in human volunteers

In a double-blind placebo controlled trial intranasal NPC 567, a bradykinin antagonist, failed to alleviate the symptoms of experimental rhinovirus colds. Indeed, there was evidence that the drug enhanced the symptoms although no irritant effect was detected on the uninfected nasal mucosa.

Detalles Bibliográficos
Autores principales: Higgins, P.G., Barrow, G.I., Tyrrell, D.A.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 1990
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7134172/
https://www.ncbi.nlm.nih.gov/pubmed/1965113
http://dx.doi.org/10.1016/0166-3542(90)90052-9