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A conditional-lethal murine coronavirus mutant that fails to incorporate the spike glycoprotein into assembled virions

The coronavirus spike glycoprotein (S) mediates both the attachment of virus to the host cell receptor and membrane fusion. We describe here the characterization of a temperature-sensitive mutant of the coronavirus mouse hepatitis virus A59 (MHV-A59) having multiple S protein-related defects. The mo...

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Detalles Bibliográficos
Autores principales: Ricard, Cynthia S., Koetzner, Cheri A., Sturman, Lawrence S., Masters, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7134215/
https://www.ncbi.nlm.nih.gov/pubmed/8837889
http://dx.doi.org/10.1016/0168-1702(95)00100-X