High-Throughput Screening Identifies Inhibitors of the SARS Coronavirus Main Proteinase

The causative agent of severe acute respiratory syndrome (SARS) has been identified as a novel coronavirus, SARS-CoV. The main proteinase of SARS-CoV, 3CL(pro), is an attractive target for therapeutics against SARS owing to its fundamental role in viral replication. We sought to identify novel inhib...

Descripción completa

Detalles Bibliográficos
Autores principales: Blanchard, Jan E., Elowe, Nadine H., Huitema, Carly, Fortin, Pascal D., Cechetto, Jonathan D., Eltis, Lindsay D., Brown, Eric D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2004
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7134594/
https://www.ncbi.nlm.nih.gov/pubmed/15489171
http://dx.doi.org/10.1016/j.chembiol.2004.08.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7134594/
https://www.ncbi.nlm.nih.gov/pubmed/15489171
http://dx.doi.org/10.1016/j.chembiol.2004.08.011

Ejemplares similares