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High-Throughput Screening Identifies Inhibitors of the SARS Coronavirus Main Proteinase

The causative agent of severe acute respiratory syndrome (SARS) has been identified as a novel coronavirus, SARS-CoV. The main proteinase of SARS-CoV, 3CL(pro), is an attractive target for therapeutics against SARS owing to its fundamental role in viral replication. We sought to identify novel inhib...

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Detalles Bibliográficos
Autores principales:	Blanchard, Jan E., Elowe, Nadine H., Huitema, Carly, Fortin, Pascal D., Cechetto, Jonathan D., Eltis, Lindsay D., Brown, Eric D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7134594/ https://www.ncbi.nlm.nih.gov/pubmed/15489171 http://dx.doi.org/10.1016/j.chembiol.2004.08.011

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