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Evaluation of metal‐conjugated compounds as inhibitors of 3CL protease of SARS‐CoV

3C‐like (3CL) protease is essential for the life cycle of severe acute respiratory syndrome‐coronavirus (SARS‐CoV) and therefore represents a key anti‐viral target. A compound library consisting of 960 commercially available drugs and biologically active substances was screened for inhibition of SAR...

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Detalles Bibliográficos
Autores principales: Hsu, John T.-A., Kuo, Chih-Jung, Hsieh, Hsing-Pang, Wang, Yeau-Ching, Huang, Kuo-Kuei, Lin, Coney P.-C., Huang, Ping-Fang, Chen, Xin, Liang, Po-Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7134601/
https://www.ncbi.nlm.nih.gov/pubmed/15358550
http://dx.doi.org/10.1016/j.febslet.2004.08.015