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Mouse hepatitis virus A59-induced demyelination can occur in the absence of CD8(+) T cells

Mouse hepatitis virus causes a chronic demyelinating disease in C57BL/6 mice. While early studies suggested demyelination is due to direct cytolytic effects of virus on oligodendrocytes, there is increasing evidence for the involvement of the immune system in the mechanism of demyelination. In this...

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Detalles Bibliográficos
Autores principales: Gombold, James L., Sutherland, Robyn M., Lavi, Ehud, Paterson, Yvonne, Weiss, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7134808/
https://www.ncbi.nlm.nih.gov/pubmed/7565015
http://dx.doi.org/10.1016/S0882-4010(95)90058-6