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Mouse hepatitis virus A59-induced demyelination can occur in the absence of CD8(+) T cells
Mouse hepatitis virus causes a chronic demyelinating disease in C57BL/6 mice. While early studies suggested demyelination is due to direct cytolytic effects of virus on oligodendrocytes, there is increasing evidence for the involvement of the immune system in the mechanism of demyelination. In this...
Autores principales: | Gombold, James L., Sutherland, Robyn M., Lavi, Ehud, Paterson, Yvonne, Weiss, Susan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ltd.
1995
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7134808/ https://www.ncbi.nlm.nih.gov/pubmed/7565015 http://dx.doi.org/10.1016/S0882-4010(95)90058-6 |
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