Cargando…

βPix-d promotes tubulin acetylation and neurite outgrowth through a PAK/Stathmin1 signaling pathway

Microtubules are a major cytoskeletal component of neurites, and the regulation of microtubule stability is essential for neurite morphogenesis. βPix (ARHGEF7) is a guanine nucleotide exchange factor for the small GTPases Rac1 and Cdc42, which modulate the organization of actin filaments and microtu...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwon, Younghee, Jeon, Ye Won, Kwon, Minjae, Cho, Yongcheol, Park, Dongeun, Shin, Jung Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135283/
https://www.ncbi.nlm.nih.gov/pubmed/32251425
http://dx.doi.org/10.1371/journal.pone.0230814