Selective imaging of solid tumours via the calcium-dependent high-affinity binding of a cyclic octapeptide to phosphorylated Annexin A2

The heterogeneity and continuous genetic adaptation of tumours complicate their detection and treatment via the targeting of genetic mutations. However, hallmarks of cancer such as aberrant protein phosphorylation and calcium-mediated cell signalling provide broadly conserved molecular targets. Here...

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Detalles Bibliográficos
Autores principales: Shen, Duanwen, Xu, Baogang, Liang, Kexian, Tang, Rui, Sudlow, Gail P., Egbulefu, Christopher, Guo, Kevin, Som, Avik, Gilson, Rebecca, Maji, Dolonchampa, Mondal, Suman, Habimana-Griffin, LeMoyne, Akers, Walter, Li, Shunqiang, Liu, Yang, Bloch, Sharon, Kurkure, Sid, Nussinov, Zohar, Seidel, Alexander, Tsen, Shaw-Wei D., Achilefu, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135742/
https://www.ncbi.nlm.nih.gov/pubmed/32165732
http://dx.doi.org/10.1038/s41551-020-0528-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135742/
https://www.ncbi.nlm.nih.gov/pubmed/32165732
http://dx.doi.org/10.1038/s41551-020-0528-7

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