Collagen I Weakly Interacts with the β-Sheets of β(2)-Microglobulin and Enhances Conformational Exchange To Induce Amyloid Formation

[Image: see text] Amyloidogenesis is significant in both protein function and pathology. Amyloid formation of folded, globular proteins is commonly initiated by partial or complete unfolding. However, how this unfolding event is triggered for proteins that are otherwise stable in their native enviro...

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Detalles Bibliográficos
Autores principales: Hoop, Cody L., Zhu, Jie, Bhattacharya, Shibani, Tobita, Caitlyn A., Radford, Sheena E., Baum, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135851/
https://www.ncbi.nlm.nih.gov/pubmed/31875390
http://dx.doi.org/10.1021/jacs.9b10421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135851/
https://www.ncbi.nlm.nih.gov/pubmed/31875390
http://dx.doi.org/10.1021/jacs.9b10421

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