Slit2 Protects Hearts Against Ischemia-Reperfusion Injury by Inhibiting Inflammatory Responses and Maintaining Myofilament Contractile Properties

BACKGROUND: The secreted glycoprotein Slit2, previously known as an axon guidance cue, has recently been found to protect tissues in pathological conditions; however, it is unknown whether Slit2 functions in cardiac ischemia–reperfusion (IR) injury. METHODS: Langendorff-perfused isolated hearts from...

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Detalles Bibliográficos
Autores principales: Li, Xiang, Zheng, Shuang, Tan, Weijiang, Chen, Hongqi, Li, Xiaohui, Wu, Jian, Luo, Ting, Ren, Xuecong, Pyle, W. Glen, Wang, Lijing, Backx, Peter H., Huang, Ren, Yang, Feng Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135862/
https://www.ncbi.nlm.nih.gov/pubmed/32292352
http://dx.doi.org/10.3389/fphys.2020.00228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135862/
https://www.ncbi.nlm.nih.gov/pubmed/32292352
http://dx.doi.org/10.3389/fphys.2020.00228

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