mPGES-1/PGE2 promotes the growth of T-ALL cells in vitro and in vivo by regulating the expression of MTDH via the EP3/cAMP/PKA/CREB pathway

T-cell acute lymphoblastic leukaemia (T-ALL) is an aggressive haematological malignancy that is characterized by a high frequency of induction failure and by early relapse. Many studies have revealed that metadherin (MTDH) is highly expressed in a variety of malignant solid tumours and plays an impo...

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Detalles Bibliográficos
Autores principales: Li, Yiqing, Chen, Jiaoting, Yang, Wenjuan, Liu, Hongyun, Wang, Jieyu, Xiao, Jie, Xie, Shuangfeng, Ma, Liping, Nie, Danian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136213/
https://www.ncbi.nlm.nih.gov/pubmed/32251289
http://dx.doi.org/10.1038/s41419-020-2380-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136213/
https://www.ncbi.nlm.nih.gov/pubmed/32251289
http://dx.doi.org/10.1038/s41419-020-2380-9

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