Generation of intestinal organoids derived from human pluripotent stem cells for drug testing

Drug absorption via the intestinal tissue is modulated by membrane permeability and metabolism in intestinal epithelial cells (IECs). In drug discovery research, using human IECs to evaluate membrane permeability and metabolic stability can offer very useful information when exploring for drug candi...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoshida, Shinpei, Miwa, Hiroto, Kawachi, Tomoyuki, Kume, Shoen, Takahashi, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136241/
https://www.ncbi.nlm.nih.gov/pubmed/32249832
http://dx.doi.org/10.1038/s41598-020-63151-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136241/
https://www.ncbi.nlm.nih.gov/pubmed/32249832
http://dx.doi.org/10.1038/s41598-020-63151-z

Ejemplares similares