A 23 bp cyp51A Promoter Deletion Associated With Voriconazole Resistance in Clinical and Environmental Isolates of Neocosmospora keratoplastica

In the fungal pathogen Aspergillus fumigatus, resistance to azole antifungals is often linked to mutations in CYP51A, a gene that encodes the azole antifungal drug target lanosterol 14α-demethylase. The aim of this study was to investigate whether similar changes could be associated with azole resis...

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Detalles Bibliográficos
Autores principales: James, Jasper Elvin, Lamping, Erwin, Santhanam, Jacinta, Milne, Trudy Jane, Abd Razak, Mohd Fuat, Zakaria, Latiffah, Cannon, Richard David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136401/
https://www.ncbi.nlm.nih.gov/pubmed/32296397
http://dx.doi.org/10.3389/fmicb.2020.00272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136401/
https://www.ncbi.nlm.nih.gov/pubmed/32296397
http://dx.doi.org/10.3389/fmicb.2020.00272

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