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5-Azacytidine Potentiates Anti-tumor Immunity in a Model of Pancreatic Ductal Adenocarcinoma

Tumors evolve a variety of mechanisms to escape immune detection while expressing tumor-promoting molecules that can be immunogenic. Here, we show that transposable elements (TE) and gene encoded, tumor-associated antigens (TAA), which can be both highly immunogenic and tumor-promoting, are signific...

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Detalles Bibliográficos
Autores principales: Ebelt, Nancy D., Zuniga, Edith, Johnson, Benjamin L., Diamond, Don J., Manuel, Edwin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136411/
https://www.ncbi.nlm.nih.gov/pubmed/32296439
http://dx.doi.org/10.3389/fimmu.2020.00538