Calcipotriol Inhibits NLRP3 Signal Through YAP1 Activation to Alleviate Cholestatic Liver Injury and Fibrosis

Cholestasis is common in multiple clinical circumstances. The NOD-like receptor protein 3 (NLRP3) inflammasome pathway has been demonstrated to play an important role in liver injury and fibrosis induced by cholestasis. We previously proved that MCC950, a selective NLRP3 inhibitor, alleviates liver...

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Detalles Bibliográficos
Autores principales: Wang, Xiaopeng, Wang, Guiyang, Qu, Junwen, Yuan, Zhiqing, Pan, Ruogu, Li, Kewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136474/
https://www.ncbi.nlm.nih.gov/pubmed/32296329
http://dx.doi.org/10.3389/fphar.2020.00200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136474/
https://www.ncbi.nlm.nih.gov/pubmed/32296329
http://dx.doi.org/10.3389/fphar.2020.00200

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