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PI(3,4)P2 Signaling in Cancer and Metabolism

The phosphatidylinositide 3 kinases (PI3Ks) and their downstream mediators AKT and mammalian target of rapamycin (mTOR) are central regulators of glycolysis, cancer metabolism, and cancer cell proliferation. At the molecular level, PI3K signaling involves the generation of the second messenger lipid...

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Detalles Bibliográficos
Autores principales: Gozzelino, Luca, De Santis, Maria Chiara, Gulluni, Federico, Hirsch, Emilio, Martini, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136497/
https://www.ncbi.nlm.nih.gov/pubmed/32296634
http://dx.doi.org/10.3389/fonc.2020.00360