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Mining Data From Plasma Cell Differentiation Identified Novel Genes for Engineering of a Yeast Antibody Factory

Saccharomyces cerevisiae is a common platform for production of therapeutic proteins, but it is not intrinsically suited for the manufacturing of antibodies. Antibodies are naturally produced by plasma cells (PCs) and studies conducted on PC differentiation provide a comprehensive blueprint for the...

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Detalles Bibliográficos
Autores principales: Koskela, Essi V., Gonzalez Salcedo, Alina, Piirainen, Mari A., Iivonen, Heidi A., Salminen, Heidi, Frey, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136540/
https://www.ncbi.nlm.nih.gov/pubmed/32296695
http://dx.doi.org/10.3389/fbioe.2020.00255