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Fibroblast Growth Factor 19 modulates intestinal microbiota and inflammation in presence of Farnesoid X Receptor

BACKGROUND: Disruption of bile acid (BA) homeostasis plays a key role in intestinal inflammation. The gut-liver axis is the main site for the regulation of BA synthesis and BA pool size via the combined action of the nuclear Farnesoid X Receptor (FXR) and the enterokine Fibroblast Growth Factor 19 (...

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Detalles Bibliográficos
Autores principales: Gadaleta, Raffaella Maria, Garcia-Irigoyen, Oihane, Cariello, Marica, Scialpi, Natasha, Peres, Claudia, Vetrano, Stefania, Fiorino, Gionatha, Danese, Silvio, Ko, Brian, Luo, Jian, Porru, Emanuele, Roda, Aldo, Sabbà, Carlo, Moschetta, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136604/
https://www.ncbi.nlm.nih.gov/pubmed/32259714
http://dx.doi.org/10.1016/j.ebiom.2020.102719