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Fibroblast Growth Factor 19 modulates intestinal microbiota and inflammation in presence of Farnesoid X Receptor
BACKGROUND: Disruption of bile acid (BA) homeostasis plays a key role in intestinal inflammation. The gut-liver axis is the main site for the regulation of BA synthesis and BA pool size via the combined action of the nuclear Farnesoid X Receptor (FXR) and the enterokine Fibroblast Growth Factor 19 (...
Autores principales: | Gadaleta, Raffaella Maria, Garcia-Irigoyen, Oihane, Cariello, Marica, Scialpi, Natasha, Peres, Claudia, Vetrano, Stefania, Fiorino, Gionatha, Danese, Silvio, Ko, Brian, Luo, Jian, Porru, Emanuele, Roda, Aldo, Sabbà, Carlo, Moschetta, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136604/ https://www.ncbi.nlm.nih.gov/pubmed/32259714 http://dx.doi.org/10.1016/j.ebiom.2020.102719 |
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