Defective nucleotide-dependent assembly and membrane fusion in Mfn2 CMT2A variants improved by Bax

Mitofusins are members of the dynamin-related protein family of large GTPases that harness the energy from nucleotide hydrolysis to remodel membranes. Mitofusins possess four structural domains, including a GTPase domain, two extended helical bundles (HB1 and HB2), and a transmembrane region. We hav...

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Detalles Bibliográficos
Autores principales: Samanas, Nyssa B, Engelhart, Emily A, Hoppins, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136618/
https://www.ncbi.nlm.nih.gov/pubmed/32245838
http://dx.doi.org/10.26508/lsa.201900527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136618/
https://www.ncbi.nlm.nih.gov/pubmed/32245838
http://dx.doi.org/10.26508/lsa.201900527

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