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Defective nucleotide-dependent assembly and membrane fusion in Mfn2 CMT2A variants improved by Bax
Mitofusins are members of the dynamin-related protein family of large GTPases that harness the energy from nucleotide hydrolysis to remodel membranes. Mitofusins possess four structural domains, including a GTPase domain, two extended helical bundles (HB1 and HB2), and a transmembrane region. We hav...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Life Science Alliance LLC
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136618/ https://www.ncbi.nlm.nih.gov/pubmed/32245838 http://dx.doi.org/10.26508/lsa.201900527 |