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Berardinelli–Seip congenital lipodystrophy 2/SEIPIN determines brown adipose tissue maintenance and thermogenic programing

OBJECTIVE: Understanding the mechanisms that control brown adipose tissue (BAT) mass and functionality is crucial for our understanding of how the disruption of energy homeostasis leads to obesity. Bernerdinali Seip Congenital Lipodystrophy (BSCL) type 2 (BSCL2, a.k.a. SEIPIN), a lipodystrophy-assoc...

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Detalles Bibliográficos
Autores principales: Zhou, Hongyi, Xu, Cheng, Lee, Hakjoo, Yoon, Yisang, Chen, Weiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136632/
https://www.ncbi.nlm.nih.gov/pubmed/32246911
http://dx.doi.org/10.1016/j.molmet.2020.02.014