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PERK Overexpression-Mediated Nrf2/HO-1 Pathway Alleviates Hypoxia/Reoxygenation-Induced Injury in Neonatal Murine Cardiomyocytes via Improving Endoplasmic Reticulum Stress

Reperfusion processes following acute myocardial infarction (AMI) have been reported to induce additional cardiomyocyte death, known as ischemia-reperfusion (I/R) injury. Endoplasmic reticulum (ER) stress is reported to be involved in the development of I/R injury. There is evidence that PERK exerts...

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Detalles Bibliográficos
Autores principales: Wang, Jichun, Lu, Li, Chen, Sisi, Xie, Jing, Lu, Shuai, Zhou, Yanli, Jiang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136769/
https://www.ncbi.nlm.nih.gov/pubmed/32309436
http://dx.doi.org/10.1155/2020/6458060