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Induction of Myogenic Differentiation Improves Chemosensitivity of Chemoresistant Cells in Soft-Tissue Sarcoma Cell Lines

Rhabdomyosarcoma (RMS) and rhabdoid tumors (RT) are rare soft-tissue malignancies with the highest incidence in infants, children, and adolescents. Advanced, recurrent, and/or metastatic RMS and RT exhibit poor response to treatment. One of the main mechanisms behind resistance to treatment is belie...

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Detalles Bibliográficos
Autores principales: Dawson, Lucy E., D'Agostino, Luca, Hakim, Abraham A., Lackman, Richard D., Brown, Spencer A., Sensenig, Richard B., Antonello, Zeus A., Kuzin, Igor I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136814/
https://www.ncbi.nlm.nih.gov/pubmed/32300280
http://dx.doi.org/10.1155/2020/8647981