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Viral replicons as valuable tools for drug discovery
RNA viruses can cause severe diseases such as dengue, Lassa, chikungunya and Ebola. Many of these viruses can only be propagated under high containment levels, necessitating the development of low containment surrogate systems such as subgenomic replicons and minigenome systems. Replicons are self-a...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Published by Elsevier Ltd.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136885/ https://www.ncbi.nlm.nih.gov/pubmed/32272194 http://dx.doi.org/10.1016/j.drudis.2020.03.010 |