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Adaptive RSK‐EphA2‐GPRC5A signaling switch triggers chemotherapy resistance in ovarian cancer

Metastatic cancers commonly activate adaptive chemotherapy resistance, attributed to both microenvironment‐dependent phenotypic plasticity and genetic characteristics of cancer cells. However, the contribution of chemotherapy itself to the non‐genetic resistance mechanisms was long neglected. Using...

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Detalles Bibliográficos
Autores principales: Moyano‐Galceran, Lidia, Pietilä, Elina A, Turunen, S Pauliina, Corvigno, Sara, Hjerpe, Elisabet, Bulanova, Daria, Joneborg, Ulrika, Alkasalias, Twana, Miki, Yuichiro, Yashiro, Masakazu, Chernenko, Anastasiya, Jukonen, Joonas, Singh, Madhurendra, Dahlstrand, Hanna, Carlson, Joseph W, Lehti, Kaisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136956/
https://www.ncbi.nlm.nih.gov/pubmed/32115889
http://dx.doi.org/10.15252/emmm.201911177