Single‐domain antibodies targeting antithrombin reduce bleeding in hemophilic mice with or without inhibitors

Novel therapies for hemophilia, including non‐factor replacement and in vivo gene therapy, are showing promising results in the clinic, including for patients having a history of inhibitor development. Here, we propose a novel therapeutic approach for hemophilia based on llama‐derived single‐domain...

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Detalles Bibliográficos
Autores principales: Barbon, Elena, Ayme, Gabriel, Mohamadi, Amel, Ottavi, Jean‐François, Kawecki, Charlotte, Casari, Caterina, Verhenne, Sebastien, Marmier, Solenne, van Wittenberghe, Laetitia, Charles, Severine, Collaud, Fanny, Denis, Cecile V, Christophe, Olivier D, Mingozzi, Federico, Lenting, Peter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136963/
https://www.ncbi.nlm.nih.gov/pubmed/32159286
http://dx.doi.org/10.15252/emmm.201911298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136963/
https://www.ncbi.nlm.nih.gov/pubmed/32159286
http://dx.doi.org/10.15252/emmm.201911298

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