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Follistatin is a novel therapeutic target and biomarker in FLT3/ITD acute myeloid leukemia

Internal tandem duplication of Fms‐like tyrosine kinase 3 (FLT3/ITD) occurs in about 30% of acute myeloid leukemia (AML) and is associated with poor response to conventional treatment and adverse outcome. Here, we reported that human FLT3/ITD expression led to axis duplication and dorsalization in a...

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Detalles Bibliográficos
Autores principales: He, Bai‐Liang, Yang, Ning, Man, Cheuk Him, Ng, Nelson Ka‐Lam, Cher, Chae‐Yin, Leung, Ho‐Ching, Kan, Leo Lai‐Hok, Cheng, Bowie Yik‐Ling, Lam, Stephen Sze‐Yuen, Wang, Michelle Lu‐Lu, Zhang, Chun‐Xiao, Kwok, Hin, Cheng, Grace, Sharma, Rakesh, Ma, Alvin Chun‐Hang, So, Chi‐Wai Eric, Kwong, Yok‐Lam, Leung, Anskar Yu‐Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7136967/
https://www.ncbi.nlm.nih.gov/pubmed/32134197
http://dx.doi.org/10.15252/emmm.201910895