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Continuous Microevolution Accelerates Disease Progression during Sequential Episodes of Infection

Bacteria adapt to dynamic changes in the host during chronic and recurrent infections. Bacterial microevolution is one type of adaptation that imparts a selective advantage. We hypothesize that recurrent episodes of disease promote microevolution through genetic mutations that modulate disease sever...

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Detalles Bibliográficos
Autores principales: Harrison, Alistair, Hardison, Rachael L., Fullen, Audra R., Wallace, Rachel M., Gordon, David M., White, Peter, Jennings, Ryan N., Justice, Sheryl S., Mason, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137071/
https://www.ncbi.nlm.nih.gov/pubmed/32130901
http://dx.doi.org/10.1016/j.celrep.2020.02.019