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Continuous Microevolution Accelerates Disease Progression during Sequential Episodes of Infection
Bacteria adapt to dynamic changes in the host during chronic and recurrent infections. Bacterial microevolution is one type of adaptation that imparts a selective advantage. We hypothesize that recurrent episodes of disease promote microevolution through genetic mutations that modulate disease sever...
Autores principales: | Harrison, Alistair, Hardison, Rachael L., Fullen, Audra R., Wallace, Rachel M., Gordon, David M., White, Peter, Jennings, Ryan N., Justice, Sheryl S., Mason, Kevin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137071/ https://www.ncbi.nlm.nih.gov/pubmed/32130901 http://dx.doi.org/10.1016/j.celrep.2020.02.019 |
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