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Mechanisms and rejuvenation strategies for aged hematopoietic stem cells

Hematopoietic stem cell (HSC) aging, which is accompanied by reduced self-renewal ability, impaired homing, myeloid-biased differentiation, and other defects in hematopoietic reconstitution function, is a hot topic in stem cell research. Although the number of HSCs increases with age in both mice an...

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Detalles Bibliográficos
Autores principales: Li, Xia, Zeng, Xiangjun, Xu, Yulin, Wang, Binsheng, Zhao, Yanmin, Lai, Xiaoyu, Qian, Pengxu, Huang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137344/
https://www.ncbi.nlm.nih.gov/pubmed/32252797
http://dx.doi.org/10.1186/s13045-020-00864-8