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Mechanisms and rejuvenation strategies for aged hematopoietic stem cells
Hematopoietic stem cell (HSC) aging, which is accompanied by reduced self-renewal ability, impaired homing, myeloid-biased differentiation, and other defects in hematopoietic reconstitution function, is a hot topic in stem cell research. Although the number of HSCs increases with age in both mice an...
Autores principales: | Li, Xia, Zeng, Xiangjun, Xu, Yulin, Wang, Binsheng, Zhao, Yanmin, Lai, Xiaoyu, Qian, Pengxu, Huang, He |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137344/ https://www.ncbi.nlm.nih.gov/pubmed/32252797 http://dx.doi.org/10.1186/s13045-020-00864-8 |
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