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Adipose stem cells from patients with Crohn’s disease show a distinctive DNA methylation pattern

BACKGROUND: Crohn’s disease (CD) is characterized by persistent inflammation and ulceration of the small or large bowel, and expansion of mesenteric adipose tissue, termed creeping fat (CF). We previously demonstrated that human adipose-derived stem cells (hASCs) from CF of patients with CD exhibit...

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Detalles Bibliográficos
Autores principales: Serena, Carolina, Millan, Monica, Ejarque, Miriam, Saera-Vila, Alfonso, Maymó-Masip, Elsa, Núñez-Roa, Catalina, Monfort-Ferré, Diandra, Terrón-Puig, Margarida, Bautista, Michelle, Menacho, Margarita, Martí, Marc, Espin, Eloy, Vendrell, Joan, Fernández-Veledo, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137346/
https://www.ncbi.nlm.nih.gov/pubmed/32252817
http://dx.doi.org/10.1186/s13148-020-00843-3