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Mechanisms of the antiplatelet and analgesic effects of dextromethorphan and its metabolites

OBJECTIVE: In the present study, we investigated the effects of dextromethorphan (DM) and its metabolites, including dextrorphan (LK2), 3-methoxymorphinan (LK3), and 3-hydroxymorphinan (LK4), on platelet aggregation in vitro and the inflammatory pain caused by carrageenan in rats, and their underlyi...

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Detalles Bibliográficos
Autores principales: Su, Wen-Lin, Weng, Yu-Ya, Huang, Wen-Hsin, Shui, Hao-Ai, Chou, Tz-Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137376/
https://www.ncbi.nlm.nih.gov/pubmed/32269947
http://dx.doi.org/10.4103/tcmj.tcmj_48_19