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Mechanisms of the antiplatelet and analgesic effects of dextromethorphan and its metabolites
OBJECTIVE: In the present study, we investigated the effects of dextromethorphan (DM) and its metabolites, including dextrorphan (LK2), 3-methoxymorphinan (LK3), and 3-hydroxymorphinan (LK4), on platelet aggregation in vitro and the inflammatory pain caused by carrageenan in rats, and their underlyi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137376/ https://www.ncbi.nlm.nih.gov/pubmed/32269947 http://dx.doi.org/10.4103/tcmj.tcmj_48_19 |