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Drug resistance occurred in a newly characterized preclinical model of lung cancer brain metastasis

BACKGROUND: Cancer metastasis and drug resistance have traditionally been studied separately, though these two lethal pathological phenomena almost always occur concurrently. Brain metastasis occurs in a large proportion of lung cancer patients (~ 30%). Once diagnosed, patients have a poor prognosis...

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Detalles Bibliográficos
Autores principales: Shah, Neal, Liu, Zhongwei, Tallman, Rachel M., Mohammad, Afroz, Sprowls, Samuel A., Saralkar, Pushkar A., Vickers, Schuyler D., Pinti, Mark V., Gao, Weimin, Lockman, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137432/
https://www.ncbi.nlm.nih.gov/pubmed/32264860
http://dx.doi.org/10.1186/s12885-020-06808-2