Synthesis, biological evaluation and molecular docking analysis of vaniline–benzylidenehydrazine hybrids as potent tyrosinase inhibitors

In this work, 11 novel compounds based on vaniline and benzylidenehydrazine structure were synthesized with various substituents on phenyl aromatic ring of the molecule and evaluated as tyrosinase inhibitors. These new derivatives showed significant anti-tyrosinase activities, among which 4i demonst...

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Detalles Bibliográficos
Autores principales: Iraji, Aida, Adelpour, Tina, Edraki, Najmeh, Khoshneviszadeh, Mahsima, Miri, Ramin, Khoshneviszadeh, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137441/
https://www.ncbi.nlm.nih.gov/pubmed/32280949
http://dx.doi.org/10.1186/s13065-020-00679-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137441/
https://www.ncbi.nlm.nih.gov/pubmed/32280949
http://dx.doi.org/10.1186/s13065-020-00679-1

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