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Pre- and post-synaptic roles for DCC in memory consolidation in the adult mouse hippocampus

The receptor deleted in colorectal cancer (DCC) and its ligand netrin-1 are essential for axon guidance during development and are expressed by neurons in the mature brain. Netrin-1 recruits GluA1-containing α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) and is critical for...

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Detalles Bibliográficos
Autores principales: Glasgow, Stephen D., Wong, Edwin W., Thompson-Steckel, Greta, Marcal, Nathalie, Séguéla, Philippe, Ruthazer, Edward S., Kennedy, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137442/
https://www.ncbi.nlm.nih.gov/pubmed/32264905
http://dx.doi.org/10.1186/s13041-020-00597-2