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Comprehensive routine diagnostic screening to identify predictive mutations, gene amplifications, and microsatellite instability in FFPE tumor material

BACKGROUND: Sensitive and reliable molecular diagnostics is needed to guide therapeutic decisions for cancer patients. Although less material becomes available for testing, genetic markers are rapidly expanding. Simultaneous detection of predictive markers, including mutations, gene amplifications a...

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Detalles Bibliográficos
Autores principales: Steeghs, Elisabeth M. P., Kroeze, Leonie I., Tops, Bastiaan B. J., van Kempen, Leon C., ter Elst, Arja, Kastner-van Raaij, Annemiek W. M., Hendriks-Cornelissen, Sandra J. B., Hermsen, Mandy J. W., Jansen, Erik A. M., Nederlof, Petra M., Schuuring, Ed, Ligtenberg, Marjolijn J. L., Eijkelenboom, Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137451/
https://www.ncbi.nlm.nih.gov/pubmed/32264863
http://dx.doi.org/10.1186/s12885-020-06785-6