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The NLRP3 inflammasome in traumatic brain injury: potential as a biomarker and therapeutic target

There is a great clinical need to identify the underlying mechanisms, as well as related biomarkers, and treatment targets, for traumatic brain injury (TBI). Neuroinflammation is a central pathophysiological feature of TBI. NLRP3 inflammasome activity is a necessary component of the innate immune re...

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Detalles Bibliográficos
Autores principales: O’Brien, William T., Pham, Louise, Symons, Georgia F., Monif, Mastura, Shultz, Sandy R., McDonald, Stuart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137518/
https://www.ncbi.nlm.nih.gov/pubmed/32252777
http://dx.doi.org/10.1186/s12974-020-01778-5