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The NLRP3 inflammasome in traumatic brain injury: potential as a biomarker and therapeutic target
There is a great clinical need to identify the underlying mechanisms, as well as related biomarkers, and treatment targets, for traumatic brain injury (TBI). Neuroinflammation is a central pathophysiological feature of TBI. NLRP3 inflammasome activity is a necessary component of the innate immune re...
Autores principales: | O’Brien, William T., Pham, Louise, Symons, Georgia F., Monif, Mastura, Shultz, Sandy R., McDonald, Stuart J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137518/ https://www.ncbi.nlm.nih.gov/pubmed/32252777 http://dx.doi.org/10.1186/s12974-020-01778-5 |
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