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Celluar Folding Determinants and Conformational Plasticity of Native C-Reactive Protein
C-reactive protein (CRP) is an acute phase reactant secreted by hepatocytes as a pentamer. The structure formation of pentameric CRP has been demonstrated to proceed in a stepwise manner in live cells. Here, we further dissect the sequence determinants that underlie the key steps in cellular folding...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137756/ https://www.ncbi.nlm.nih.gov/pubmed/32296446 http://dx.doi.org/10.3389/fimmu.2020.00583 |