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Histone demethylase KDM3B protects against ferroptosis by upregulating SLC7A11

Ferroptosis is a type of adaptive cell death driven by cellular metabolism and iron‐dependent lipid peroxidation. Though multiple genes (including SLC7A11 and GPX4) have been demonstrated to play key roles in ferroptosis, little is known about the epigenetic regulation of this process. Here, we repo...

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Detalles Bibliográficos
Autores principales: Wang, Yishu, Zhao, Yao, Wang, Haihua, Zhang, Chengliang, Wang, Meiqi, Yang, Yong, Xu, Xin, Hu, Zhenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137800/
https://www.ncbi.nlm.nih.gov/pubmed/32107878
http://dx.doi.org/10.1002/2211-5463.12823