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Early Induction of Cross-Reactive CD8(+) T-Cell Responses in Tonsils After Live-Attenuated Influenza Vaccination in Children

BACKGROUND: Live-attenuated influenza vaccine (LAIV) was licensed for prophylaxis of children 2–17 years old in Europe in 2012 and is administered as a nasal spray. Live-attenuated influenza vaccine induces both mucosal and systemic antibodies and systemic T-cell responses. Tonsils are the lymph nod...

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Detalles Bibliográficos
Autores principales: Mohn, K G-I, Brokstad, K A, Islam, S, Oftung, F, Tøndel, C, Aarstad, H J, Cox, R J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137893/
https://www.ncbi.nlm.nih.gov/pubmed/32255493
http://dx.doi.org/10.1093/infdis/jiz583