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Early Induction of Cross-Reactive CD8(+) T-Cell Responses in Tonsils After Live-Attenuated Influenza Vaccination in Children
BACKGROUND: Live-attenuated influenza vaccine (LAIV) was licensed for prophylaxis of children 2–17 years old in Europe in 2012 and is administered as a nasal spray. Live-attenuated influenza vaccine induces both mucosal and systemic antibodies and systemic T-cell responses. Tonsils are the lymph nod...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137893/ https://www.ncbi.nlm.nih.gov/pubmed/32255493 http://dx.doi.org/10.1093/infdis/jiz583 |