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An Equivocal Final Link – Quantitative Determination of the Thermodynamic Efficiency of ATP Hydrolysis – Sullies the Chain of Electric, Ionic, Mechanical and Metabolic Steps Underlying Cardiac Contraction

Each beat of the heart completes the final step in a sequence of events commencing with electrical excitation-triggered release of Ca(2+) from the sarcoplasmic reticulum which, in turn, triggers ATP-hydrolysis-dependent mechanical contraction. Given that Thermodynamics is inherently detail-independe...

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Detalles Bibliográficos
Autores principales: Barclay, Christopher John, Loiselle, Denis Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137898/
https://www.ncbi.nlm.nih.gov/pubmed/32296338
http://dx.doi.org/10.3389/fphys.2020.00183