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An Equivocal Final Link – Quantitative Determination of the Thermodynamic Efficiency of ATP Hydrolysis – Sullies the Chain of Electric, Ionic, Mechanical and Metabolic Steps Underlying Cardiac Contraction
Each beat of the heart completes the final step in a sequence of events commencing with electrical excitation-triggered release of Ca(2+) from the sarcoplasmic reticulum which, in turn, triggers ATP-hydrolysis-dependent mechanical contraction. Given that Thermodynamics is inherently detail-independe...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137898/ https://www.ncbi.nlm.nih.gov/pubmed/32296338 http://dx.doi.org/10.3389/fphys.2020.00183 |