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Specificity in PDZ-peptide interaction networks: Computational analysis and review

Globular PDZ domains typically serve as protein–protein interaction modules that regulate a wide variety of cellular functions via recognition of short linear motifs (SLiMs). Often, PDZ mediated-interactions are essential components of macromolecular complexes, and disruption affects the entire scaf...

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Detalles Bibliográficos
Autores principales: Amacher, Jeanine F., Brooks, Lionel, Hampton, Thomas H., Madden, Dean R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138185/
https://www.ncbi.nlm.nih.gov/pubmed/32289118
http://dx.doi.org/10.1016/j.yjsbx.2020.100022